Human CD8(+)CD28(−) T suppressor cells expanded by common gamma chain (γc) cytokines retain steady allospecific suppressive capacity in vivo

BACKGROUND: CD8(+)CD28(−) T suppressor (Ts) cells play critical role in transplant tolerance. Our previous study has generated CD8(+)CD28(−) Ts cells in vitro which exert robust allospecific suppressive capacity in vitro. RESULTS: CD8(+)CD28(−) Ts cells were expanded by stimulating human CD8(+) T ce...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Liu, Guihuan, Yu, Yuming, Feng, Fu, Zhu, Ping, Zhang, Hua, Zhang, Danni, Feng, Xiaoqiang, Zhang, Zedan, Liu, Yanjun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189520/
https://ncbi.nlm.nih.gov/pubmed/32349664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-020-00354-z
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