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LSD1 inhibition yields functional insulin-producing cells from human embryonic stem cells

BACKGROUND: Human embryonic stem cells represent a potentially unlimited source of insulin-producing cells for diabetes therapy. While tremendous progress has been made in directed differentiation of human embryonic stem cells into IPCs in vitro, the mechanisms controlling its differentiation and fu...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: He, Fei, Li, Ning, Huang, Hai-Bo, Wang, Jing-Bo, Yang, Xiao-Fei, Wang, Hua-Dong, Huang, Wei, Li, Fu-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189473/
https://ncbi.nlm.nih.gov/pubmed/32345350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01674-y
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