Interplay of erythropoietin, fibroblast growth factor 23, and erythroferrone in patients with hereditary hemolytic anemia

Recently, erythropoietin (EPO) was identified as regulator of fibroblast growth factor 23 (FGF23). Proteolytic cleavage of biologically active intact FGF23 (iFGF23) results in the formation of C-terminal fragments (cFGF23). An increase in cFGF23 relative to iFGF23 suppresses FGF receptor signaling b...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: van Vuren, Annelies. J., Eisenga, Michele F., van Straaten, Stephanie, Glenthøj, Andreas, Gaillard, Carlo A. J. M., Bakker, Stephan J. L., de Borst, Martin H., van Wijk, Richard, van Beers, Eduard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189297/
https://ncbi.nlm.nih.gov/pubmed/32324886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001595
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