Therapeutic Antibody Against Phosphorylcholine Preserves Coronary Function and Attenuates Vascular (18)F-FDG Uptake in Atherosclerotic Mice

This study showed that treatment with a therapeutic monoclonal immunoglobulin-G1 antibody against phosphorylcholine on oxidized phospholipids preserves coronary flow reserve and attenuates atherosclerotic inflammation as determined by the uptake of (18)F-fluorodeoxyglucose in atherosclerotic mice. T...

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Gepubliceerd in:JACC Basic Transl Sci
Hoofdauteurs: Ståhle, Mia, Silvola, Johanna M.U., Hellberg, Sanna, de Vries, Margreet, Quax, Paul H.A., Kroon, Jeffrey, Rinne, Petteri, de Jong, Alwin, Liljenbäck, Heidi, Savisto, Nina, Wickman, Anna, Stroes, Erik S.G., Ylä-Herttuala, Seppo, Saukko, Pekka, Abrahamsson, Tommy, Pettersson, Knut, Knuuti, Juhani, Roivainen, Anne, Saraste, Antti
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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PRECLINICAL RESEARCH
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188869/
https://ncbi.nlm.nih.gov/pubmed/32368695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.01.008
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