Long-term potentiation prevents ketamine-induced aberrant neurophysiological dynamics in the hippocampus-prefrontal cortex pathway in vivo

N-methyl-D-aspartate receptor (NMDAr) antagonists such as ketamine (KET) produce psychotic-like behavior in both humans and animal models. NMDAr hypofunction affects normal oscillatory dynamics and synaptic plasticity in key brain regions related to schizophrenia, particularly in the hippocampus and...

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Vydáno v:Sci Rep
Hlavní autoři: Lopes-Aguiar, Cleiton, Ruggiero, Rafael N., Rossignoli, Matheus T., Esteves, Ingrid de Miranda, Peixoto-Santos, José Eduardo, Romcy-Pereira, Rodrigo N., Leite, João P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188848/
https://ncbi.nlm.nih.gov/pubmed/32346044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63979-5
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