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Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive soft-tissue malignancy with a poor overall survival and no effective therapeutic options. The tumor is believed to be dependent on the continued activity of the oncogenic EWS-WT1 transcription factor. However, the dependence of the...

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Dettagli Bibliografici
Pubblicato in:Oncogenesis
Autori principali: Gedminas, Jenna M., Chasse, Maggie H., McBrairty, Mitchell, Beddows, Ian, Kitchen-Goosen, Susan M., Grohar, Patrick J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188842/
https://ncbi.nlm.nih.gov/pubmed/32345977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-0224-1
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