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Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages

The enteric nervous system (ENS) predominantly originates from vagal neural crest cells (VNC) that emerge from the caudal hindbrain, invade the foregut and populate the gastrointestinal tract. However, the gene regulatory network (GRN) orchestrating the early specification of VNC remains unknown. Us...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Ling, Irving TC, Sauka-Spengler, Tatjana
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188519/
https://ncbi.nlm.nih.gov/pubmed/31792380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0428-9
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