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Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages

The enteric nervous system (ENS) predominantly originates from vagal neural crest cells (VNC) that emerge from the caudal hindbrain, invade the foregut and populate the gastrointestinal tract. However, the gene regulatory network (GRN) orchestrating the early specification of VNC remains unknown. Us...

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Publicado en:Nat Cell Biol
Autores principales: Ling, Irving TC, Sauka-Spengler, Tatjana
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188519/
https://ncbi.nlm.nih.gov/pubmed/31792380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0428-9
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