Evocalcet prevents ectopic calcification and parathyroid hyperplasia in rats with secondary hyperparathyroidism

BACKGROUND: Elevated parathyroid hormone (PTH) levels in secondary hyperparathyroidism (SHPT) lead to vascular calcification, which is associated with cardiovascular events and mortality. Increased PTH production is caused by the excessive proliferation of parathyroid gland cells, which is accelerat...

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Veröffentlicht in:PLoS One
Hauptverfasser: Sakai, Mariko, Tokunaga, Shin, Kawai, Mika, Murai, Miki, Kobayashi, Misaki, Kitayama, Tetsuya, Saeki, Satoshi, Kawata, Takehisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188245/
https://ncbi.nlm.nih.gov/pubmed/32343734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232428
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