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COVID-19 vaccine design: the Janus face of immune enhancement

Previous work on severe acute respiratory syndrome coronavirus (SARS-CoV) vaccines identified cellular immunopathology and antibody-dependent enhancement as potential safety issues. We discuss the implications of these findings for COVID-19 vaccine development and our approach to optimizing for safe...

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Detalhes bibliográficos
Publicado no:Nat Rev Immunol
Main Authors: Hotez, Peter J., Corry, David B., Bottazzi, Maria Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187801/
https://ncbi.nlm.nih.gov/pubmed/32346094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-020-0323-4
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