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The Sle1 Cell Wall Amidase Is Essential for β-Lactam Resistance in Community-Acquired Methicillin-Resistant Staphylococcus aureus USA300

Most clinically relevant methicillin-resistant Staphylococcus aureus (MRSA) strains have become resistant to β-lactams antibiotics through horizontal acquisition of the mecA gene encoding PBP2a, a peptidoglycan transpeptidase with low affinity for β-lactams. The level of resistance conferred by mecA...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Thalsø-Madsen, Ida, Torrubia, Fernando Ruiz, Xu, Lijuan, Petersen, Andreas, Jensen, Camilla, Frees, Dorte
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187620/
https://ncbi.nlm.nih.gov/pubmed/31685469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01931-19
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