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Activity of Meropenem with a Novel Broader-Spectrum β-Lactamase Inhibitor, WCK 4234, against Gram-Negative Pathogens Endemic to New York City

WCK 4234 is a novel diazabicyclooctane with potent inhibitory activity against class A and D carbapenemases and class C enzymes. We examined the in vitro activity of meropenem plus WCK 4234 (4 or 8 μg/ml) against Gram-negative pathogens from New York City. Three groups of isolates were analyzed: a c...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Iregui, Alejandro, Khan, Zeb, Landman, David, Quale, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187611/
https://ncbi.nlm.nih.gov/pubmed/31611363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01666-19
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