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Synthesis of the 8,19‐Epoxysteroid Eurysterol A

We report the first chemical synthesis of eurysterol A, a cytotoxic and antifungal marine steroidal sulfate with a unique C8−C19 oxy‐bridged cholestane skeleton. After C19 hydroxylation of cholesteryl acetate, used as an inexpensive commercial starting material, the challenging oxidative functionali...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Taspinar, Ömer, Wilczek, Tobias, Erver, Julian, Breugst, Martin, Neudörfl, Jörg‐Martin, Schmalz, Hans‐Günther
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187428/
https://ncbi.nlm.nih.gov/pubmed/32031278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202000585
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