Positron Emission Tomography Imaging With [(18)F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes

IMPORTANCE: Positron emission tomography (PET) may increase the diagnostic accuracy and confirm the underlying neuropathologic changes of Alzheimer disease (AD). OBJECTIVE: To determine the accuracy of antemortem [(18)F]flortaucipir PET images for predicting the presence of AD-type tau pathology at...

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Vydáno v:JAMA Neurol
Hlavní autoři: Fleisher, Adam S., Pontecorvo, Michael J., Devous, Michael D., Lu, Ming, Arora, Anupa K., Truocchio, Stephen P., Aldea, Patricia, Flitter, Matthew, Locascio, Tricia, Devine, Marybeth, Siderowf, Andrew, Beach, Thomas G., Montine, Thomas J., Serrano, Geidy E., Curtis, Craig, Perrin, Allison, Salloway, Stephen, Daniel, Misty, Wellman, Charles, Joshi, Abhinay D., Irwin, David J., Lowe, Val J., Seeley, William W., Ikonomovic, Milos D., Masdeu, Joseph C., Kennedy, Ian, Harris, Thomas, Navitsky, Michael, Southekal, Sudeepti, Mintun, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2020
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186920/
https://ncbi.nlm.nih.gov/pubmed/32338734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2020.0528
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