Enhanced glutamine utilization mediated by SLC1A5 and GPT2 is an essential metabolic feature of colorectal signet ring cell carcinoma with therapeutic potential

BACKGROUND: Colorectal signet-ring cell carcinoma (SRCC) is characterized as a rare subset of colorectal cancer with extremely poor prognosis and it is known to have low or negative (18)F fluorodeoxyglucose ((18)F-FDG) uptake. To date, no in-depth study revealing the metabolic features of colorectal...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Wang, Renjie, Xiang, Wenqiang, Xu, Ye, Han, Lingyu, Li, Qingguo, Dai, Weixing, Cai, Guoxiang
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186745/
https://ncbi.nlm.nih.gov/pubmed/32355746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2020.03.31
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