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Circular RNA circNRIP1 Sponges microRNA-138-5p to Maintain Hypoxia-Induced Resistance to 5-Fluorouracil Through HIF-1α-Dependent Glucose Metabolism in Gastric Carcinoma

BACKGROUND: Hypoxia-induced chemoresistance is recognized as a major obstacle to the successful treatment of gastric cancer (GC). Circular RNAs (circRNAs) have been proposed to implicate in resistance to chemotherapeutic drugs. However, whether circNRIP1 is involved in the development of hypoxia-ind...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Xu, Guangsong, Li, Mingliang, Wu, Jiang, Qin, Chunhong, Tao, Yin, He, Hongjie
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186590/
https://ncbi.nlm.nih.gov/pubmed/32425596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S246272
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