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Multigene Panel Testing Provides a New Perspective on Lynch Syndrome

PURPOSE: Most existing literature describes Lynch syndrome (LS) as a hereditary syndrome leading to high risks of colorectal cancer (CRC) and endometrial cancer mainly as a result of mutations in MLH1 and MSH2. Most of these studies were performed on cohorts with disease suggestive of hereditary CRC...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Espenschied, Carin R., LaDuca, Holly, Li, Shuwei, McFarland, Rachel, Gau, Chia-Ling, Hampel, Heather
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186580/
https://ncbi.nlm.nih.gov/pubmed/28514183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.71.9260
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