Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR

The C-type lectin receptors (CLRs) form a family of pattern recognition receptors that recognize numerous pathogens, such as bacteria and fungi, and trigger innate immune responses. The extracellular carbohydrate-recognition domain (CRD) of CLRs forms a globular structure that can coordinate a Ca(2+...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Omahdi, Zakaria, Horikawa, Yuto, Nagae, Masamichi, Toyonaga, Kenji, Imamura, Akihiro, Takato, Koichi, Teramoto, Takamasa, Ishida, Hideharu, Kakuta, Yoshimitsu, Yamasaki, Sho
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186165/
https://ncbi.nlm.nih.gov/pubmed/32139512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012491
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