Cell cycle oscillators underlying orderly proteolysis of E2F8

E2F8 is a transcriptional repressor that antagonizes E2F1 at the crossroads of the cell cycle, apoptosis, and cancer. Previously, we discovered that E2F8 is a direct target of the APC/C ubiquitin ligase. Nevertheless, it remains unknown how E2F8 is dynamically controlled throughout the entirety of t...

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Publié dans:Mol Biol Cell
Auteurs principaux: Wasserman, Danit, Nachum, Sapir, Cohen, Meital, Enrico, Taylor P., Noach-Hirsh, Meirav, Parasol, Jasmin, Zomer-Polak, Sarit, Auerbach, Naomi, Sheinberger-Chorni, Evelin, Nevenzal, Hadas, Levi-Dadon, Nofar, Wang, Xianxi, Lahmi, Roxane, Michaely, Efrat, Gerber, Doron, Emanuele, Michael J., Tzur, Amit
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2020
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185961/
https://ncbi.nlm.nih.gov/pubmed/31995441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-12-0725
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