Epimedium-derived phytoestrogen exert beneficial effect on preventing steroid-associated osteonecrosis in rabbits with inhibition of both thrombosis and lipid-deposition

OBJECTIVES: This study tested the effect of Epimedium-derived phytoestrogen (PE) on preventing steroid-associated osteonecrosis (ON) in rabbit model. METHODS: Thirty 28-week-old male New-Zealand white rabbits were divided into control group (CON; n = 14) and PE group (PE; n = 16; 5 mg/kg body weight...

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Vydáno v:Bone
Hlavní autoři: Zhang, G., Qin, L., Sheng, H., Yeung, K.W., Yeung, H.Y., Cheung, W.H., Griffith, J., Chan, C.W., Lee, K.M., Leung, K.S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Inc. 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185875/
https://ncbi.nlm.nih.gov/pubmed/17188589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2006.10.026
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