Manipulating angiotensin metabolism with angiotensin converting enzyme 2 (ACE2) in heart failure

Angiotensin converting enzyme 2 (ACE2), is a monocarboxypeptidase which metabolizes several peptides including the degradation of Ang II, a peptide with vasoconstrictive/proliferative/effects, to generate Ang 1–7, which acting through its receptor Mas exerts vasodilatory/anti-proliferative actions....

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Detalles Bibliográficos
Publicado en:Drug Discov Today Ther Strateg
Autores principales: Patel, Vaibhav B., Putko, Brendan, Wang, Zuocheng, Zhong, Jiu-Chang, Oudit, Gavin Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Ltd. 2012
Materias:
Heart Failure
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185729/
https://ncbi.nlm.nih.gov/pubmed/32362932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddstr.2013.11.001
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