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The Eukaryotic Translation Initiation Factor 4E (eIF4E) as a Therapeutic Target for Cancer
Cancer cells depend on cap-dependent translation more than normal tissue. This explains the emergence of proteins involved in the cap-dependent translation as targets for potential anticancer drugs. Cap-dependent translation starts when eIF4E binds to mRNA cap domain. This review will present eIF4E&...
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| Publicado no: | Adv Protein Chem Struct Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7185574/ https://ncbi.nlm.nih.gov/pubmed/26572974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apcsb.2015.09.001 |
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