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Heterologous Boosting of Recombinant Adenoviral Prime Immunization With a Novel Vesicular Stomatitis Virus–vectored Tuberculosis Vaccine

Pulmonary tuberculosis (TB) remains a serious health problem worldwide. Effective vaccination strategies are needed. We report the development of a novel TB vaccine using vesicular stomatitis virus (VSV) as a viral vector system to express Ag85A. VSVAg85A was shown to be immunogenic when given to mi...

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Publicado en:Mol Ther
Main Authors: Roediger, Elizabeth K, Kugathasan, Kapilan, Zhang, XiZhong, Lichty, Brian D, Xing, Zhou
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Gene Therapy. Published by Elsevier Inc. 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185538/
https://ncbi.nlm.nih.gov/pubmed/18388911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.59
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