A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver

The liver is the largest solid organ and a primary metabolic hub. In recent years, intact cell nuclei were used to perform single-nuclei RNA-seq (snRNA-seq) for tissues difficult to dissociate and for flash-frozen archived tissue samples to discover unknown and rare cell subpopulations. In this stud...

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Dettagli Bibliografici
Pubblicato in:OMICS
Autori principali: Cavalli, Marco, Diamanti, Klev, Pan, Gang, Spalinskas, Rapolas, Kumar, Chanchal, Deshmukh, Atul Shahaji, Mann, Matthias, Sahlén, Pelin, Komorowski, Jan, Wadelius, Claes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2020
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185313/
https://ncbi.nlm.nih.gov/pubmed/32181701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/omi.2019.0215
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