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Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells

Platinum-taxane combination chemotherapy still represents the standard of care for advanced non-small cell lung cancer (NSCLC) with no targetable driver mutations. However, the efficacy of these drugs has plateaued at 10–14 months primarily due to dose-limiting toxicity, chemoresistance, and metasta...

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Publicado en:Oncotarget
Autores principales: Kyakulaga, Al Hassan, Aqil, Farrukh, Munagala, Radha, Gupta, Ramesh C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185067/
https://ncbi.nlm.nih.gov/pubmed/32362998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27519
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