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Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal

Rhabdomyosarcoma (RMS) is the most common soft-tissue pediatric sarcoma. Clinical outcomes for RMS patients with relapsed or metastatic disease remain poor. Treatment options remain limited, presenting an urgent need for novel therapeutic targets. Using a high-throughput siRNA screen against the hum...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pham, Thao, Robinson, Kristin, Vleeshouwer-Neumann, Terra, Annis, James E., Chen, Eleanor Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185065/
https://ncbi.nlm.nih.gov/pubmed/32363002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27562
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