Long-Term Implant Fibrosis Prevention in Rodents and Non-Human Primates Using Localized Deliverable Crystals

Implantable medical devices have revolutionized modern medicine. However, immune-mediated foreign body response (FBR) to the materials of these devices can limit their function or even induce failure. Here we describe long-term controlled release formulations for local anti-inflammatory release thro...

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Gepubliceerd in:Nat Mater
Hoofdauteurs: Farah, Shady, Doloff, Joshua C., Müller, Peter, Sadraei, Atieh, Han, Hye Jung, Olafson, Katy, Vyas, Keval, Tam, Hok Hei, Hollister-Locke, Jennifer, Kowalski, Piotr S., Griffin, Marissa, Meng, Ashley, McAvoy, Malia, Graham, Adam C., McGarrigle, James, Oberholzer, Jose, Weir, Gordon C., Greiner, Dale L., Langer, Robert, Anderson, Daniel G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184801/
https://ncbi.nlm.nih.gov/pubmed/31235902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-019-0377-5
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