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Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei

BACKGROUND: Vacuolar H(+)-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles. Beyond its role in pH maintenance, the involvement of V-ATPase in endocytosis is well documented in mammals and plants but is less clear in Trypanoso...

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Foilsithe in:Parasit Vectors
Main Authors: Xu, Zhi-Shen, Li, Feng-Jun, Hide, Geoff, Lun, Zhao-Rong, Lai, De-Hua
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183646/
https://ncbi.nlm.nih.gov/pubmed/32334612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-020-04068-4
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