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Dexmedetomidine Preconditioning Protects Rats from Renal Ischemia–Reperfusion Injury Accompanied with Biphasic Changes of Nuclear Factor-Kappa B Signaling

Acute kidney injury (AKI) is one of the most common and troublesome perioperative complications. Dexmedetomidine (DEX) is a potent α2-adrenoceptor (α2-AR) agonist with anti-inflammatory and renoprotective effects. In this study, a rat renal ischemia–reperfusion injury (IRI) model was induced. At 24 ...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Bao, Naren, Tang, Bing, Wang, Junke
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183529/
https://ncbi.nlm.nih.gov/pubmed/32377532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3230490
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