Toxicity of a combined therapy using the mTOR-inhibitor everolimus and PRRT with [(177)Lu]Lu-DOTA-TATE in Lewis rats

PURPOSE: Peptide receptor radionuclide therapy (PRRT) with [(177)Lu]Lu-DOTA(0),TYR(3)-octreotate ([(177)Lu]Lu-DOTA-TATE) and the mechanistic target of rapamycin (mTOR) inhibitor everolimus are both approved for the treatment of neuroendocrine tumours (NET). However, tumour progression is still frequ...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Zellmer, Johannes, Yen, Hsi-Yu, Kaiser, Lena, Mille, Erik, Gildehaus, Franz Josef, Böning, Guido, Steiger, Katja, Hacker, Marcus, Bartenstein, Peter, Todica, Andrei, Haug, Alexander R., Ilhan, Harun
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183514/
https://ncbi.nlm.nih.gov/pubmed/32335736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-020-00628-y
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