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Significant association between tumor mutational burden and immune-related adverse events during immune checkpoint inhibition therapies
More than 2000 immuno-oncology agents are being tested or are in use as a result of the cancer immunotherapy revolution. Manipulation of co-inhibitory receptors has achieved tumor eradication in a minority of patients, but widespread immune-related adverse events (irAEs) compromised tolerance to hea...
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| Publicado no: | Cancer Immunol Immunother |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7183506/ https://ncbi.nlm.nih.gov/pubmed/32152702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02543-6 |
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