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Talimogene laherparepvec treatment to overcome loco-regional acquired resistance to immune checkpoint blockade in tumor stage IIIB–IV M1c melanoma patients

BACKGROUND: Resistance to immune checkpoint blockade and targeted therapy in melanoma patients is currently one of the major clinical challenges. With the approval of talimogene laherparepvec (T-VEC), oncolytic viruses are now in clinical practice for locally advanced or non-resectable melanoma. Her...

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Bibliografski detalji
Izdano u:Cancer Immunol Immunother
Glavni autori: Fröhlich, Anne, Niebel, Dennis, Fietz, Simon, Egger, Eva, Buchner, Andrea, Sirokay, Judith, Landsberg, Jennifer
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183503/
https://ncbi.nlm.nih.gov/pubmed/32052079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02487-x
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