Swinhopeptolides A and B: Cyclic Depsipeptides from the Sponge Theonella swinhoei that Inhibit Ras/Raf Interaction

Two new cyclic depsipeptides named swinhopeptolides A (1) and B (2), have been isolated from the marine sponge Theonella swinhoei cf. verrucosa, collected from Papua New Guinea. They each contain 11 diverse amino acid resudues and 13-carbon polyketide moieties attached at the N-terminus. Compounds 1...

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Vydáno v:J Nat Prod
Hlavní autoři: Kim, Chang-Kwon, Wang, Dongdong, Bokesch, Heidi R., Fuller, Richard W., Smith, Emily, Henrich, Curtis J., Durrant, David E., Morrison, Deborah K., Bewley, Carole A., Gustafson, Kirk R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183427/
https://ncbi.nlm.nih.gov/pubmed/32191460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.0c00136
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