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An in vitro tissue model for screening sustained release of phosphate-based therapeutics in attenuating pathogen-induced proteolytic matrix degradation

Tissue response to intestinal injury or disease releases pro-inflammatory host stress signals triggering microbial shift to pathogenic phenotypes. One such phenotype is increased protease production resulting in collagen degradation and activation of host matrix metalloproteinases contributing to ti...

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Bibliografiske detaljer
Udgivet i:J Mater Chem B
Main Authors: Pimentel, Marja B., Borges, Fernando T.P., Teymour, Fouad, Zaborina, Olga Y., Alverdy, John C., Fang, Kuili, Hong, Seok Hoon, Staneviciute, Austeja, He, Yusheng J., Papavasiliou, Georgia
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183213/
https://ncbi.nlm.nih.gov/pubmed/32108210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9tb02356a
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