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Transcribed B lymphocyte genes and multiple sclerosis risk genes are underrepresented in Epstein–Barr Virus hypomethylated regions

Epstein–Barr Virus (EBV) infection appears to be necessary for the development of Multiple Sclerosis (MS), although the specific mechanisms are unknown. More than 200 single-nucleotide polymorphisms (SNPs) are known to be associated with the risk of developing MS. About a quarter of these are also h...

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Vydáno v:Genes Immun
Hlavní autoři: Ong, Lawrence T. C., Parnell, Grant P., Afrasiabi, Ali, Stewart, Graeme J., Swaminathan, Sanjay, Booth, David R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182534/
https://ncbi.nlm.nih.gov/pubmed/31619767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-019-0089-5
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