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The importance of B cell receptor isotypes and stereotypes in Chronic Lymphocytic Leukemia
B cell receptor (BCR) signaling is a central pathway promoting the survival and proliferation of normal and malignant B cells. Chronic lymphocytic leukemia (CLL) arises from mature B cells, expressing functional BCRs, mainly of IgM and IgD isotypes. Importantly, 30% of CLL patients express quasi-ide...
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| Veröffentlicht in: | Leukemia |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7182338/ https://ncbi.nlm.nih.gov/pubmed/30555163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0303-x |
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