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No Genotoxicity Is Detectable for Escherichia coli Strain Nissle 1917 by Standard In Vitro and In Vivo Tests

Probiotic Escherichia coli strain Nissle 1917 (EcN) has a long history of safe use. However, the recently discovered presence of a pks locus in its genome presumably producing colibactin has questioned its safety, as colibactin has been implicated in genotoxicity. Here, we assess the genotoxic poten...

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Détails bibliographiques
Publié dans:Eur J Microbiol Immunol (Bp)
Auteurs principaux: Dubbert, Silke, Klinkert, Birgit, Schimiczek, Michael, Wassenaar, Trudy M., von Bünau, Rudolf
Format: Artigo
Langue:Inglês
Publié: Akadémiai Kiadó 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182118/
https://ncbi.nlm.nih.gov/pubmed/32363034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1556/1886.2019.00025
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