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Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein

The naked mole-rat is a subterranean rodent, approximately the size of a mouse, renowned for its exceptional longevity (>30 years) and remarkable resistance to cancer. To explore putative mechanisms underlying the cancer resistance of the naked mole-rat, we investigated the regulation and functio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Deuker, Marian M., Lewis, Kaitlyn N., Ingaramo, Maria, Kimmel, Jacob, Buffenstein, Rochelle, Settleman, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181817/
https://ncbi.nlm.nih.gov/pubmed/32332849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64009-0
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