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A necroptotic-independent function of MLKL in regulating endothelial cell adhesion molecule expression

Mixed-lineage kinase domain-like protein (MLKL) is known as the terminal executor of necroptosis. However, its function outside of necroptosis is still not clear. Herein, we demonstrate that MLKL promotes vascular inflammation by regulating the expression of adhesion molecules ICAM1, VCAM1, and E-se...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Principais autores: Dai, Jialin, Zhang, Chonghe, Guo, Lin, He, Hao, Jiang, Kai, Huang, Yingying, Zhang, Xixi, Zhang, Haibing, Wei, Wu, Zhang, Yaoyang, Lu, Lihua, Hu, Junhao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181788/
https://ncbi.nlm.nih.gov/pubmed/32332696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2483-3
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