Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis

Gut microbial dysbiosis is associated with the development of autoimmune disease, but the mechanisms by which microbial dysbiosis affects the transition from asymptomatic autoimmunity to inflammatory disease are incompletely characterized. Here, we identify intestinal barrier integrity as an importa...

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Vydáno v:Nat Commun
Hlavní autoři: Tajik, Narges, Frech, Michael, Schulz, Oscar, Schälter, Fabian, Lucas, Sébastien, Azizov, Vugar, Dürholz, Kerstin, Steffen, Franziska, Omata, Yasunori, Rings, Andreas, Bertog, Marko, Rizzo, Aroldo, Iljazovic, Aida, Basic, Marijana, Kleyer, Arnd, Culemann, Stephan, Krönke, Gerhard, Luo, Yubin, Überla, Klaus, Gaipl, Udo S., Frey, Benjamin, Strowig, Till, Sarter, Kerstin, Bischoff, Stephan C., Wirtz, Stefan, Cañete, Juan D., Ciccia, Francesco, Schett, Georg, Zaiss, Mario M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181728/
https://ncbi.nlm.nih.gov/pubmed/32332732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15831-7
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