Cardiac remodeling and arrhythmogenesis are ameliorated by administration of Cx43 mimetic peptide Gap27 in heart failure rats

Alterations in connexins and specifically in 43 isoform (Cx43) in the heart have been associated with a high incidence of arrhythmogenesis and sudden death in several cardiac diseases. We propose to determine salutary effect of Cx43 mimetic peptide Gap27 in the progression of heart failure. High-out...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Lucero, Claudia M., Andrade, David C., Toledo, Camilo, Díaz, Hugo S., Pereyra, Katherin V., Diaz-Jara, Esteban, Schwarz, Karla G., Marcus, Noah J., Retamal, Mauricio A., Quintanilla, Rodrigo A., Del Rio, Rodrigo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181683/
https://ncbi.nlm.nih.gov/pubmed/32327677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63336-6
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