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Anti-CD81 antibodies reduce migration of activated T lymphocytes and attenuate mouse experimental colitis

Inflammatory bowel disease (IBD) is an immunological disease associated with CD4(+) T cell activation in the intestines. CD81 is a regulator of the immune system with multiple biological functions. Therefore, in this study, we assessed the contribution of CD81 to IBD pathophysiology and the therapeu...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Hasezaki, Takuya, Yoshima, Tadahiko, Mine, Yukiko
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181603/
https://ncbi.nlm.nih.gov/pubmed/32332834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64012-5
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