Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours

BACKGROUND: Testicular germ cell tumours (TGCTs) are characterised by an overall high cisplatin-sensitivity which has been linked to their continued expression of pluripotency factors. Recently, the Nodal signalling pathway has been implicated in the regulation of pluripotency factor expression in f...

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Publicat a:BMC Cancer
Autors principals: Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, U. N., Rasmussen, L. J., Blomberg Jensen, M., Mitchell, R. T., Juul, A., Rajpert-De Meyts, E., Jørgensen, A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181506/
https://ncbi.nlm.nih.gov/pubmed/32326899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06820-6
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