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Intratumor heterogeneity: the Rosetta stone of therapy resistance

Advances in our understanding of molecular mechanisms of tumorigenesis have translated into knowledge-based therapies directed against specific oncogenic signaling targets. These therapies often induce dramatic responses in susceptible tumors. Unfortunately, most advanced cancers, including those wi...

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Pubblicato in:Cancer Cell
Autori principali: Marusyk, Andriy, Janiszewska, Michalina, Polyak, Kornelia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181408/
https://ncbi.nlm.nih.gov/pubmed/32289271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.03.007
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