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Intratumor heterogeneity: the Rosetta stone of therapy resistance

Advances in our understanding of molecular mechanisms of tumorigenesis have translated into knowledge-based therapies directed against specific oncogenic signaling targets. These therapies often induce dramatic responses in susceptible tumors. Unfortunately, most advanced cancers, including those wi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Cell
Hauptverfasser: Marusyk, Andriy, Janiszewska, Michalina, Polyak, Kornelia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181408/
https://ncbi.nlm.nih.gov/pubmed/32289271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.03.007
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