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Theoretical Studies Aimed at Finding FLT3 Inhibitors and a Promising Compound and Molecular Pattern with Dual Aurora B/FLT3 Activity

FLT3 and dual Aurora B/FLT3 inhibitors have shown relevance in the search for promising new anticancer compounds, mainly for acute myeloid leukemia (AML). This study was designed to investigate the interactions between human FLT3 in the kinase domain with several indolin−2-one derivatives, structura...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Fernandes, Ítalo Antônio, Braga Resende, Déborah, Ramalho, Teodorico Castro, Kuca, Kamil, da Cunha, Elaine Fontes Ferreira
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181172/
https://ncbi.nlm.nih.gov/pubmed/32283751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071726
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