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Theoretical Studies Aimed at Finding FLT3 Inhibitors and a Promising Compound and Molecular Pattern with Dual Aurora B/FLT3 Activity

FLT3 and dual Aurora B/FLT3 inhibitors have shown relevance in the search for promising new anticancer compounds, mainly for acute myeloid leukemia (AML). This study was designed to investigate the interactions between human FLT3 in the kinase domain with several indolin−2-one derivatives, structura...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Fernandes, Ítalo Antônio, Braga Resende, Déborah, Ramalho, Teodorico Castro, Kuca, Kamil, da Cunha, Elaine Fontes Ferreira
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181172/
https://ncbi.nlm.nih.gov/pubmed/32283751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071726
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