Comparison of high and low molar activity TSPO tracer [(18)F]F-DPA in a mouse model of Alzheimer’s disease

[(18)F]F-DPA, a novel translocator protein 18 kDa (TSPO)-specific radioligand for imaging neuroinflammation, has to date been synthesized with low to moderate molar activities (A(m)’s). In certain cases, low A(m) can skew the estimation of specific binding. The high proportion of the non-radioactive...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Keller, Thomas, López-Picón, Francisco R, Krzyczmonik, Anna, Forsback, Sarita, Takkinen, Jatta S, Rajander, Johan, Teperi, Simo, Dollé, Frédéric, Rinne, Juha O, Haaparanta-Solin, Merja, Solin, Olof
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181084/
https://ncbi.nlm.nih.gov/pubmed/31142224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19853117
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