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Extracellular ASC exacerbated the recurrent ischemic stroke in an NLRP3-dependent manner
Using a photothrombotic mouse model of single stroke, we show that a single stroke onset increases the nuclear factor-κB (NF-κB), NLR family CARD domain containing protein 4 (NLRC4), and absent in melanoma 2 (AIM2) inflammasomes, as well as the mRNA levels of NLRP3. Next, using a photothrombotic mou...
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| Publicado no: | J Cereb Blood Flow Metab |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7181081/ https://ncbi.nlm.nih.gov/pubmed/31216943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19856226 |
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