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Molecular mechanism of acquired drug resistance in the EGFR‐TKI resistant cell line HCC827‐TR

BACKGROUND: The first‐line standard treatment of non‐small cell lung cancer (NSCLC) with EGFR mutation is EGFR‐tyrosine kinase inhibitors (TKIs). However, most patients will develop acquired resistance after 9–13 months. This study investigated novel molecular mechanisms of acquired resistance to EG...

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Pubblicato in:Thorac Cancer
Autori principali: Yu, Tao, Xia, Qian, Gong, Ting, Wang, Jing, Zhong, DianSheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons Australia, Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180561/
https://ncbi.nlm.nih.gov/pubmed/32163227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13342
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