Systemic Immune Modulation in Gliomas: Prognostic Value of Plasma IL-6, YKL-40, and Genetic Variation in YKL-40

Background: Complex local and systemic immune dysfunction in glioblastoma (GBM) may affect survival. Interleukin (IL)-6 and YKL-40 are pleiotropic biomarkers present in the tumor microenvironment and involved in immune regulation. We therefore analyzed plasma IL-6, YKL-40, and genetic variation in Y...

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Udgivet i:Front Oncol
Main Authors: Holst, Camilla Bjørnbak, Christensen, Ib Jarle, Skjøth-Rasmussen, Jane, Hamerlik, Petra, Poulsen, Hans Skovgaard, Johansen, Julia Sidenius
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180208/
https://ncbi.nlm.nih.gov/pubmed/32363159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00478
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