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Fibrin-VLDL receptor-dependent pathway promotes leukocyte transmigration by inhibiting Src kinase Fyn and is a target for fibrin β15–42 peptide
According to the current view, binding of fibrin degradation product E(1) fragment to endothelial VE-cadherin promotes transendothelial migration of leukocytes and thereby inflammation, and fibrin-derived β15–42 peptide reduces leukocyte transmigration by competing with E(1) for binding to VE-cadher...
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| Udgivet i: | Thromb Haemost |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7179994/ https://ncbi.nlm.nih.gov/pubmed/31466086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1695008 |
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