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Burosumab versus continuation of conventional therapy in children with X-linked hypophosphatemia: a randomised, active-controlled, open-label, phase 3 trial
BACKGROUND: X-linked hypophosphatemia in children is characterized by elevated serum FGF23, hypophosphatemia, rickets, lower extremity bowing, and growth impairment. We compared the efficacy and safety of continuing conventional therapy, consisting of oral phosphate and active vitamin D, versus swit...
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| 出版年: | Lancet |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7179969/ https://ncbi.nlm.nih.gov/pubmed/31104833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(19)30654-3 |
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